Richard Simon

Results: 156



#Item
91Computational statistics / Resampling / Bootstrapping / Cross-validation / Variance / Sample size determination / Bootstrap aggregating / Statistics / Statistical inference / Data analysis

A comparison of bootstrap methods and an adjusted bootstrap approach for estimating prediction error in microarray classification Short title: Bootstrap Prediction Error Estimation Wenyu Jiang* and Richard Simon

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:33
92Microarrays / Gene expression / Machine learning / DNA / Genomics / Gene expression profiling / Oncotype DX / Significance analysis of microarrays / DNA microarray / Biology / Medicine / Genetics

Interpretation of Genomic Data: Questions and Answers Richard Simon Using a question and answer format we describe important aspects of using genomic technologies in cancer research. The main challenges are not managing

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:34
93Bootstrapping / Resampling / Cross-validation / Normal distribution / Sample size determination / Statistical hypothesis testing / Gene expression profiling / Prediction interval / Margin of error / Statistics / Statistical inference / Confidence interval

Original Paper Gene Expression Calculating Confidence Intervals for Prediction Error in Microarray Classification Using Resampling Wenyu Jiang*§, Sudhir Varma§ and Richard Simon§

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:24
94Epidemiology / Clinical research / Design of experiments / Pharmacology / Evaluation methods / Biomarker / Oncotype DX / Imaging biomarker / Clinical trial / Medicine / Health / Chemistry

CCR FOCUS The Use of Genomics in Clinical Trial Design Richard Simon Abstract

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:18
95Molecular biology / RNA / Gene expression / Bioinformatics / Gene expression profiling / DNA microarray / DNA / Functional genomics / Gene expression profiling in cancer / Biology / Genetics / Microarrays

Design Issues in DNA Microarray Based Studies Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute [removed]

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:28
96Water / Sea surface temperature / Expendable bathythermograph / Buoy / Climate / CLIMAT / Error / Oceanography / Atmospheric sciences / Meteorology

A Project to Create Bias-Corrected Marine Climate Observations from ICOADS Shawn R. Smith1, Mark A. Bourassa1, Scott Woodruff2, Steve Worley3, Elizabeth Kent4, Simon Josey4, Nick Rayner5, and Richard Reynolds6 1Center

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Source URL: icoads.noaa.gov

Language: English - Date: 2008-08-03 13:03:45
97Gene expression / BRCA1 / Bioinformatics / Antibody microarray / Tiling array / Biology / Microarrays / DNA microarray

Genetic Epidemiology 23:21–[removed]Design of Studies Using DNA Microarrays Richard Simon,* Michael D. Radmacher, and Kevin Dobbin Biometric Research Branch, National Cancer Institute, Bethesda, Maryland DNA microarr

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:35
98Oncology / Oncotype DX / Machine learning / Tamoxifen / Breast cancer / Biomarker / Gene expression profiling / Statistical classification / MammaPrint / Medicine / Medical tests / Microarrays

EDITORIALS Development and Evaluation of Therapeutically Relevant Predictive Classifiers Using Gene Expression Profiling Richard Simon Gene expression profiles offer the possibility of improving risk predication and opti

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:29
99Bioinformatics / Gene expression / Molecular biology / Regression analysis / Gene expression profiling / Cross-validation / DNA microarray / Logistic regression / Statistics / Microarrays / Biology

Technical Report 001 July 1, 2001 A Paradigm for Class Prediction Using Gene Expression Profiles Michael D. Radmacher, Lisa M. McShane and Richard Simon

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:35
100Estimation theory / Data analysis / Monte Carlo methods / Cross-validation / Resampling / Bootstrapping / Mean squared error / Regression analysis / Estimator / Statistics / Statistical inference / Computational statistics

Prediction Error Estimation: A Comparison of Resampling Methods Annette M. Molinaro ∗ Biostatistics Branch Division of Cancer Epidemiology and Genetics, NCI, NIH Richard Simon

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Source URL: linus.nci.nih.gov

Language: English - Date: 2013-03-12 10:01:36
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